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JAVMA Publishes Vida Pharmacal Paper

1 August, 2019

JAVMA published Dr. Madigan’s investigation of using amiodarone and itraconazole to treat Chagas disease. Check out the August 1 issue of JAVMA.

PAHO Issues New Guide for Diagnosis and Treatment of Chagas Disease

14 January, 2019

To improve detection and management of the disease, the Pan American Health Organization (PAHO) has published a new Guide for Diagnosis and Treatment of Chagas Disease (currently available only in Spanish).

Chagas Disease in Working Dogs Along Texas-Mexico Border

3 November, 2018

Chagas disease, caused by the vector-borne protozoan Trypanosoma cruzi, is increasingly recognized in the southern U.S. Government-owned working dogs along the Texas-Mexico border could be at heightened risk.

Drug for ‘neglected’ Chagas disease gains FDA approval amid price worries

10 September, 2017

The Food and Drug Administration recently approved the first U.S. treatment for childhood cases of Chagas disease — a parasite-driven illness that, over time and unless treated early, can cause serious heart problems in about a third of the people it infects.

A New Strategy to Undermine Big Pharma’s Price Gouging Actually Worked

7 September, 2017

A little-known disease called Chagas is much more prevalent than Zika. Here’s how advocates fought an uphill battle, and won.

FDA approves first U.S. treatment for Chagas disease

29 August, 2017

The U.S. Food and Drug Administration today granted accelerated approval to benznidazole for use in children ages 2 to 12 years old with Chagas disease. It is the first treatment approved in the United States for the treatment of Chagas disease.

Papers

PCR Monitoring of Parasitemia During Drug Treatment for Canine Chagas Disease

Published on August 5, 2019

Vida Pharmacal participated in a study that monitored its treatment effectiveness using two real-time assays. Published in Sage Journals, August 5, 2019.

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Investigation of a combination of amiodarone and itraconazole for treatment of American trypanosomiasis (Chagas disease) in dogs, JAVMA

Published on August 1, 2019

The purpose of the study reported here was to evaluate the clinical, serologic, parasitological, and histopathologic outcomes of dogs naturally infected with T cruzi and treated with a combination of itraconazole and amiodarone for 12 months.

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Human Stem Cell-Derived Cardiomyocytes and Chagas

Published on June 17, 2019

Human pluripotent stem cells were differentiated into cardiomyocytes and infected with T. cruzi to test efficacy of combined ICZ and AMD dosage.

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