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The Silent Killer: More than a bug bite

19 September, 2019

Dr. Roy Madigan was interviewed by News4 San Antonio in an article about T Cruzi.

JAVMA Publishes Vida Pharmacal Paper

1 August, 2019

JAVMA published Dr. Madigan’s investigation of using amiodarone and itraconazole to treat Chagas disease. Check out the August 1 issue of JAVMA.

PAHO Issues New Guide for Diagnosis and Treatment of Chagas Disease

14 January, 2019

To improve detection and management of the disease, the Pan American Health Organization (PAHO) has published a new Guide for Diagnosis and Treatment of Chagas Disease (currently available only in Spanish).

Chagas Disease in Working Dogs Along Texas-Mexico Border

3 November, 2018

Chagas disease, caused by the vector-borne protozoan Trypanosoma cruzi, is increasingly recognized in the southern U.S. Government-owned working dogs along the Texas-Mexico border could be at heightened risk.

A New Strategy to Undermine Big Pharma’s Price Gouging Actually Worked

7 September, 2017

A little-known disease called Chagas is much more prevalent than Zika. Here’s how advocates fought an uphill battle, and won.

Hunting Hidden Parasites: Trypanosoma cruzi

19 August, 2017

Pathogens are not aware of international borders, including pathogens that cause emerging and neglected tropical diseases. Although Chagas disease is endemic to Latin America, where it affects around 5.7 million people, it is now a disease of global concern mainly because of the movement of human populations. The original article can be found at https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)31536-2/fulltext.

Papers

The effects of formulation on the pharmacokinetics of itraconazole and amiodarone in dogs after oral administration of a combination product, commercial products, and compounded products

Published on October 11, 2023

Vida teamed in a study that evaluated four different formulations of itraconazole and amiodarone. The study was published in the Wiley Journal of Veterinary Pharmacology and Therapeutics.

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PCR Monitoring of Parasitemia During Drug Treatment for Canine Chagas Disease

Published on August 5, 2019

Vida Pharmacal participated in a study that monitored its treatment effectiveness using two real-time assays. Published in Sage Journals, August 5, 2019.

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Investigation of a combination of amiodarone and itraconazole for treatment of American trypanosomiasis (Chagas disease) in dogs, JAVMA

Published on August 1, 2019

The purpose of the study reported here was to evaluate the clinical, serologic, parasitological, and histopathologic outcomes of dogs naturally infected with T cruzi and treated with a combination of itraconazole and amiodarone for 12 months.

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