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News

PAHO Issues New Guide for Diagnosis and Treatment of Chagas Disease

14 January, 2019

To improve detection and management of the disease, the Pan American Health Organization (PAHO) has published a new Guide for Diagnosis and Treatment of Chagas Disease (currently available only in Spanish).

Chagas Disease in Working Dogs Along Texas-Mexico Border

3 November, 2018

Chagas disease, caused by the vector-borne protozoan Trypanosoma cruzi, is increasingly recognized in the southern U.S. Government-owned working dogs along the Texas-Mexico border could be at heightened risk.

Drug for ‘neglected’ Chagas disease gains FDA approval amid price worries

10 September, 2017

The Food and Drug Administration recently approved the first U.S. treatment for childhood cases of Chagas disease — a parasite-driven illness that, over time and unless treated early, can cause serious heart problems in about a third of the people it infects.

Recent Press Releases

5 August, 2019

Vida Pharmacal Delivers First Cure for Canine Chagas Disease

Author: Roy Madigan

Vida Pharmacal today announced the first cure for canine Chagas disease. Its multicenter field study, Successful Treatment of Canine Chagas Disease, was published in the prestigious Journal of the American Veterinary Medical Association, August 1, 2019.

23 March, 2018

New Company, Vida Pharmacal, Formed to Develop Cure for Chagas Disease

Authors: Roy Madigan, Roy Madigan

Vida Pharmacal, the first pharmaceutical company devoted to developing, marketing, and distributing a treatment for Chagas disease in veterinary patients, today announced its official launch.

Videos

16 March, 2018

Zoe's Story

Length: 1 minute, 38 seconds

Zoe - "Yellow Collar Girl"'s - journey through Chagas disease.

8 January, 2018

The Science of The Heart

Length: 16 seconds

Nobody—canine or human—was harmed to make this video! In this clip, you’ll see beating human heart cells that were cultured from umbilical cord embryonic stem cells.

Our scientific testing methodology explored the use of Vidarone and its effect on trypanosomiasis in human cardiac stem cells. This short video shows beating human heart cells grown in a lab dish. The technique allows researchers to identify genetic mutations, test drugs, and advance understanding of cardiac disease.

Papers

PCR Monitoring of Parasitemia During Drug Treatment for Canine Chagas Disease

Published on August 5, 2019

Vida Pharmacal participated in a study that monitored its treatment effectiveness using two real-time assays. Published in Sage Journals, August 5, 2019.

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Investigation of a combination of amiodarone and itraconazole for treatment of American trypanosomiasis (Chagas disease) in dogs, JAVMA

Published on August 1, 2019

The purpose of the study reported here was to evaluate the clinical, serologic, parasitological, and histopathologic outcomes of dogs naturally infected with T cruzi and treated with a combination of itraconazole and amiodarone for 12 months.

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Human Stem Cell-Derived Cardiomyocytes and Chagas

Published on June 17, 2019

Human pluripotent stem cells were differentiated into cardiomyocytes and infected with T. cruzi to test efficacy of combined ICZ and AMD dosage.

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